Croton macrostachyus. Euphorbiaceae. Hochst. ex Ferret et Galinier. C. macrostachys: A representative tree at. Kakuzi Ranch, Kenya. (Paul K.A. Konuche). Croton macrostachyus Hochst. ex Delile is a species of the genus Croton L., Euphorbiaceae family, commonly known as the spurge family. In Kenya, leaves and roots from Croton macrostachyus are used as a traditional medicine for infectious diseases such as typhoid and measles.

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The stem bark and twigs contain lupeol, betulin and several fatty acids. The dynamics of drug resistance in Plasmodium falciparium.

There are citation in web searches related to Croton macrostachyus Hochst. For example, in Ethiopia, macrostachyuw bark decoction of C. View at Google Scholar C. The percent parasitemia and the erythrocytes were counted using the white blood cell count method.

Agricultural Research Reports The methanol extract against E.

Croton macrostachyus Hochst. ex Delile

A tree reference and selection guide version 4. Croton macrostachyus Croton macrostachyus x – 19k – jpg www. King, Plants of Deep South Texas: The crude ground seeds showed high molluscicidal activity in vitro. Stem barks and twigs of Croton spp.

The average parasitemia was calculated as. The improvements can be attributed to WHO-recommended core interventions, vector control, chemoprevention, diagnostic testing, and treatment, which all have proven to be cost-effective. NMR analysis of the ethyl acetate extract from C. Macrostacgyus Tanzania, fruit and decoction of C. In our study, two- four- and tenfold higher macrostachyuss of lupeol in the ethyl acetate extract predominant compound of The crystals were analyzed by NMR spectroscopy.

The selection of antibiotics and antifungal agents was based on the general knowledge of the typical susceptibilities of the chosen indicator microorganisms, and the expected sensitivities were confirmed during the actual experiments.


Agar well diffusion method [ 12 ] was used to determine the zones of inhibition and the MIC values. The results obtained in the present study revealed that C. However, further investigations are needed aimed at identifying chemical constituents of C.

For the test groups an oral dose of 0. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

View at Google Scholar I. The Nubian goat kids were allotted as untreated controls and ground C.

There are 20 citations in Afrirefs related to Croton macrostachyus Hochst. Support Center Support Center. NMR analysis of the fractionated and crystallized ethyl acetate extract was carried out. Consent to use the experimental animals in the study was obtained from the ethical committee of the Kenya Medical Research Institute, Center of Biotechnology and Research Development, Department of Malaria.

Publisher Royal Botanic Gardens; Kew. Croton macrostachyus tree habit CopyLeft EcoPort. Activity of lupeol from the leaf hexane extract of Vernonia brasiliana L. Aqueous leaf extract of C. There was a correlation between changes of the erythrocyte membrane shape to stomatocytic form and the inhibition of Plasmodium falciparum growth caused by a tropical plant Rinorea ilicifolia Kuntze lupeol in vitro [ 25 ].

Conclusions The results obtained in the present study revealed that C. National Center for Biotechnology InformationU. Tropical Plants Database, Ken Fern. The fresh stem bark was cut into small pieces using a pen knife. Evaluation of antimalarial activity of leaves of Acokanthera schimperi and Croton macrostachyus against Plasmodium berghei in Swiss albino mice.


There are both negative and positive reports on the antibacterial activity of methanol extracts from C. The preparation is taken with pepper, butter and milk. Similarly, Bantie et al.

Evidence-Based Complementary and Alternative Medicine

These pharmacological activities include anthelmintic [ 3095 ], antibacterial [ 535562859296 — ], anticonvulsant and sedative [ 50 ], antidiabetic [ 88 ], antidiarrhoeal [ 24 ], antifungal [ 628692], anti-inflammatory [ 84], antileishmanial [ 94 ], antioxidant [ 86 ], antiplasmodial [ 8789, ], antimycobacterial [ ], larvicidal [ 1950 ], and cytotoxicity [ 27437396— ].

Inflorescence a slender, terminal raceme up to 35 cm long, either with only male or female flowers or male and female flowers variably mixed. Flavonoids and phenolic compounds found in plants are known to have antioxidant properties [ ].

Pharmacological studies have also focused on evaluating anthelmintic, antibacterial, antimycobacterial, antidiarrhoeal, antifungal, anticonvulsant and sedative, antidiabetic, anti-inflammatory, antileishmanial, antioxidant, antiplasmodial, larvicidal, and cytotoxicity activities of the different extracts and compounds isolated from C.

Further testing of the active components of C. Croton macrostachyus is a medium sized, drought-deciduous pioneer tree which regenerates naturally in less productive sites including forest edges, mountain slopes, and waste grounds under a wide range of ecological conditions [ macrostacnyus — 3 ]. Therefore, the results suggest that C.

Croton macrostachyus

Both aqueous and hydroalcoholic extracts of C. A preparation of the seed is instilled into the ear to treat ear problems. Preparation of Parasites Plasmodium berghei strain ANKA, a chloroquine-sensitive strain of malaria parasite, was used in the in vivo study.